drugset / Trial / NCT04987372
Multimodal Versus Opioid aNalgesia in carDiAc Surgery
RandomizedParallel-groupSingle-blindTreatment
Summary
To compare standard "Fentanyl - Tramadol - Paracetamol - Oxycodone" regimen to a multimodal painmanagement "pregabalin- minimal fentanyl-ketamine-lidocain-dexmedetomidine- paracetamol" to determine which therapy provides the most comfort, the fastest extubation time, the least pain and the least delirium.
Timeline
- Start
- 2019-01-21
- Primary completion
- 2021-12-01
- Completion
- 2021-12-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexmedetomidine | Other / unclassified | 0.8 ug/kg | Intravenous |
| Comparator | Ketamine | Small molecule | 0.3 mg/kg | Intravenous |
| Comparator | Lidocaine | Other / unclassified | 1.3 mg/kg | Intravenous |
| Comparator | Magnesium Sulfate | Other / unclassified | 25 mg/kg | Intravenous |
| Comparator | Pregabalin | Small molecule | 75 mg | Oral |