drugset / Trial / NCT05006638
Assessing The Role Of Intravenous Lipid Emulsion As A Life Saving Therapy In Pesticides Toxicity
RandomizedParallel-groupOpen-labelSupportive care
Summary
Intravenous lipid emulsion is an established, effective treatment for local anesthetic systemic toxicity. It is also efficacious in animal models of severe cardiotoxicity caused by a number of other medications. Recent case reports of successful resuscitation suggest the efficacy of lipid emulsion infusion for treating non-local anesthetic overdoses across a wide spectrum of drugs. The present study will focus on the potential role of intravenous lipid emulsion as an adjuvant therapy in pesticides toxicity.
Timeline
- Start
- 2022-12
- Primary completion
- 2023-06
- Completion
- 2023-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Lipid Emulsion | Unknown | 1.5 unknown | Intravenous |
| Comparator | Atropine | Other / unclassified | — | — |
| Comparator | Ondansetron | Other / unclassified | — | — |
| Comparator | Toxogonin | Unknown | — | — |
| Comparator | sodium bicarbonate | Diagnostic / imaging agent | — | — |