drugset / Trial / NCT05218733

Ultrasound Guided Erector Spinae Plane Block vs Intrathecal Morphine

NCT05218733 ↗

Phase 4 Completed 120 enrolled Ain Shams University
RandomizedParallel-groupDouble-blindPrevention

Summary

Total abdominal hysterectomy (TAH) is a major surgical procedure after which significant post-operative pain and discomfort are anticipated. Abdominal field blocks have been followed for many years and extensively used for pain management following abdominal surgeries such as laparotomies and appendicectomies. Erector Spinae Plane Block (ESPB)-first recently described for the treatment of thoracic neuropathic pain, is a peri-paravertebral regional anesthesia technique that has since been reported as an effective technique for prevention of postoperative pain in various surgeries. Intrathecal opioid administration is an attractive analgesic technique since the opioid is injected directly into the cerebrospinal fluid, close to the structures of the central nervous system where the opioid acts.

Timeline

Start
2022-02-15
Primary completion
2023-09-20
Completion
2023-09-20

Drugs

EvaluationDrugModalityDoseRoute
Comparator Morphine Other / unclassified 300 ug Intrathecal
Background Fentanyl Other / unclassified 1 ug/kg Intravenous

Indications

No indication recorded.