drugset / Trial / NCT05242874
Anti-emetic Prophylaxis With or Without Dexamethasone
RandomizedParallel-groupOpen-labelTreatment
Summary
To evaluate the efficacy and safety of a fosaprepitant, tropisetron, and olanzapine antiemetic regimen, with or without dexamethasone, in patients receiving highly emetogenic chemotherapy with epirubicin and cyclophosphamide.
Timeline
- Start
- 2022-02-01
- Primary completion
- 2023-08-15
- Completion
- 2023-08-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexamethasone | Small molecule | 8 mg | — |
| Background | Fosaprepitant | Other / unclassified | 150 mg | Intravenous |
| Background | Olanzapine | Small molecule | 5 mg | Oral |
| Background | Tropisetron | Small molecule | 5 mg | Intravenous |