Subacromial Injection of Epinephrine Improves Visualization in Shoulder Arthroscopy

Phase 4 Completed 60 enrolled The University of Texas Health Science Center, Houston

RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to evaluate surgeon-rated visual clarity and the need for increased irrigation pump pressure during arthroscopic shoulder surgery and to evaluate mean arterial pressure, operative time, and any adverse events that occur during arthroscopic shoulder surgery.

Timeline

Start: 2022-03-14
Primary completion: 2022-08-31
Completion: 2022-08-31

Outcome

Missed primary endpoint

paper visual clarity was slightly better in the epinephrine group compared with the control group, although the difference was neither statistically nor clinically significant PMID 39399770 ↗

paper 8.3 ± 1.4 vs 7.5 ± 1.8, respectively; P = .09 PMID 39399770 ↗

Publications

Feinstein S, Svetgoff RA, Harmon J, Siahaan J, Ngo DH, Fullick RK, Flores SE, Shupe PG, Gregory BP, Gregory JM. Effect of a Preoperative Subacromial Epinephrine Injection on Visualization During Shoulder Arthroscopic Surgery: A Randomized Controlled Trial. Orthop J Sports Med. 2024 Oct 10;12(10):23259671241278247. doi: 10.1177/23259671241278247. eCollection 2024 Oct.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Epinephrine	Other / unclassified	0.3 ml	Other
Background	Bupivacaine	Other / unclassified	0.5 %	Other

Indications

No indication recorded.