drugset / Trial / NCT05270200

Single Arm Study of Post-transplant Azacitidine and Chidamide for Prevention of Acute Myelogenous Leukemia Relapse

NCT05270200

Phase 1/2 Recruiting 40 enrolled Zhujiang Hospital
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical research study is to learn if azacitidine combined with Chidamide will help to control the disease in patients with high-risk AML after an allogeneic stem cell transplant. The safety of this combination will also be studied.

Timeline

Start
2022-02-01
Primary completion
2027-12-31
Completion
2027-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Azacitidine Other / unclassified 50 mg/m2
Subject Tucidinostat Small molecule 5 mg