drugset / Trial / NCT05340231
An Exploratory Study of Sequential Transarterial Chemoembolization With Lipiodol and Neoadjuvant Chemotherapy in the Treatment of Initial Unresectable Colorectal Cancer (CRC)
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a prospective, open-labelled study to evaluate the efficacy and safety of sequetial transarterial chemoembolization with lipiodol and neoadjuvant chemotherapy in the treatment of initial unresectable colorectal cancer. The progression-free-survival (PFS) will be evaluated as the primary endpoints.
Timeline
- Start
- 2022-05-01
- Primary completion
- 2022-12-31
- Completion
- 2025-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Oxaliplatin | Small molecule | 85 mg/m2 | Other |
| Subject | Oxaliplatin | Small molecule | 85 mg | Other |
| Subject | Raltitrexed | Small molecule | 3 mg | Other |
| Subject | lipiodol | Unknown | 10 ml | Other |
| Background | Lidocaine | Other / unclassified | 1 ml | — |