drugset / Trial / NCT05372354

A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma

NCT05372354

Phase 1/2 Recruiting 260 enrolled Bristol-Myers Squibb
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the safety, tolerability and preliminary effectiveness of CC-92480 (BMS-986348) in novel therapeutic combinations for the treatment of Relapsed or Refractory Multiple Myeloma (RRMM).

Timeline

Start
2022-10-18
Primary completion
2026-10-12
Completion
2026-10-12

Drugs

EvaluationDrugModalityDoseRoute
Subject EZOBRESIB Small molecule
Subject Mezigdomide Small molecule
Subject Tazemetostat Small molecule
Subject Trametinib Small molecule
Background Dexamethasone Small molecule

Indications