Enhanced Versus Extended Preoperative Antibiotic Prophylaxis Regimens for Retrograde Intrarenal Surgery in High Infectious Risk Patients

Summary

In the available literature, there is a lack the risk categorization of infectious complications after RIRS with subsequent recommendation as regard to AP in different risk patients. Therefore this study is planning to investigate the optimal protocol for AP prior to RIRS in high-risk population through comparing the enhanced regimen (2days) vs. the extended regimen (7 days) in a randomized controlled trial (RCT).

Timeline

Start

2022-05-01

Primary completion

2023-05-01

Completion

2023-07-01

Publications

• Elsawy AA, Nour EA, Nabeeh A, El-Nahas AR. Enhanced versus extended preoperative antibiotic prophylaxis for retrograde intrarenal surgery in high infectious risk patients: a randomized controlled trial. World J Urol. 2025 Dec 29;44(1):70. doi: 10.1007/s00345-025-06150-x.

Drugs

Indications