drugset / Trial / NCT05510323
Efficacy of Immunosuppressive Therapy for IgA Nephropathy With Stage 3 or 4 CKD
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this clinical trial is to evaluate the long-term efficacy and safety of low-dose oral corticosteroids combined with cyclophosphamide therapy and low-dose corticosteroids monotherapy, on a background of maximal RAS inhibitor therapy, for IgA nephropathy with stage 3 or 4 chronic kidney disease.
Timeline
- Start
- 2024-02-01
- Primary completion
- 2025-08
- Completion
- 2028-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cyclophosphamide | Other / unclassified | — | — |
| Comparator | Prednisolone | Other / unclassified | — | — |