drugset / Trial / NCT05519813

Effects of Pioglitazone Combined With Metformin on Gonadal and Metabolic Profiles in Chinese Nonobese PCOS Patients.

NCT05519813

Phase 4 Unknown 60 enrolled Bing He
RandomizedParallel-groupOpen-labelTreatment

Summary

To study the effects of pioglitazone combined with metformin and metformin on gonadal and metabolic profiles in PCOS patients with BMI \< 24 in China. 60 cases of nonobese PCOS patients were collected from Shengjing hospital. The intervention period was 3 months after intervention with met or met + ph. To evaluate the improvement of met or met + ph in the treatment of hyperandremia, glucose metabolism, BMI, waist circumference, menstruation, hairiness and acne in PCOS patients.

Timeline

Start
2022-01-01
Primary completion
2023-01-01
Completion
2023-03-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Metformin Small molecule 500 mg
Subject Metformin Small molecule 1500 mg
Subject Metformin Small molecule 2000 mg
Subject Pioglitazone Small molecule 15 mg