drugset / Trial / NCT05519813
Effects of Pioglitazone Combined With Metformin on Gonadal and Metabolic Profiles in Chinese Nonobese PCOS Patients.
RandomizedParallel-groupOpen-labelTreatment
Summary
To study the effects of pioglitazone combined with metformin and metformin on gonadal and metabolic profiles in PCOS patients with BMI \< 24 in China. 60 cases of nonobese PCOS patients were collected from Shengjing hospital. The intervention period was 3 months after intervention with met or met + ph. To evaluate the improvement of met or met + ph in the treatment of hyperandremia, glucose metabolism, BMI, waist circumference, menstruation, hairiness and acne in PCOS patients.
Timeline
- Start
- 2022-01-01
- Primary completion
- 2023-01-01
- Completion
- 2023-03-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metformin | Small molecule | 500 mg | — |
| Subject | Metformin | Small molecule | 1500 mg | — |
| Subject | Metformin | Small molecule | 2000 mg | — |
| Subject | Pioglitazone | Small molecule | 15 mg | — |