drugset / Trial / NCT05523102

Paracetamol Compared With Ketorolac for Post-operative Analgetic

NCT05523102

RandomizedParallel-groupDouble-blindTreatment

Summary

Post-operative analgetic modalities vary between center to center, especially in Indonesia. Considerations include potency/effectivity of the analgetics to achieve adequate pain control as soon as possible, reducing the total opioid dose intake and overall reducing potential opioid adverse effects. NSAID have been known to have more adverse effects than acetaminophen (paracetamol) but offers a higher potency for analgetic effects. Here the investigators compare whether paracetamol is adequate as a post-operative analgetics and confers fewer overall adverse effects when compared with ketorolac (NSAID)

Timeline

Start
2022-03-31
Primary completion
2022-07-18
Completion
2022-08-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Acetaminophen Small molecule 15 mg/kg Intravenous
Comparator Ketorolac Other / unclassified 0.5 mg/kg Intravenous

Indications