drugset / Trial / NCT05523102
Paracetamol Compared With Ketorolac for Post-operative Analgetic
RandomizedParallel-groupDouble-blindTreatment
Summary
Post-operative analgetic modalities vary between center to center, especially in Indonesia. Considerations include potency/effectivity of the analgetics to achieve adequate pain control as soon as possible, reducing the total opioid dose intake and overall reducing potential opioid adverse effects. NSAID have been known to have more adverse effects than acetaminophen (paracetamol) but offers a higher potency for analgetic effects. Here the investigators compare whether paracetamol is adequate as a post-operative analgetics and confers fewer overall adverse effects when compared with ketorolac (NSAID)
Timeline
- Start
- 2022-03-31
- Primary completion
- 2022-07-18
- Completion
- 2022-08-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acetaminophen | Small molecule | 15 mg/kg | Intravenous |
| Comparator | Ketorolac | Other / unclassified | 0.5 mg/kg | Intravenous |