drugset / Trial / NCT05577260
The Effect of Intraperitoneal Injection of Magnesium Sulphate Versus Dexmedetomidine as an Adjuvant to Bupivacaine on Postoperative Analgesia in Patients Undergoing Abdominal Aortic Surgery
RandomizedParallel-groupDouble-blindSupportive care
Summary
optimal management of postoperative pain is essentiel for better outcome in abdominal aortic surgery.the study aim to compare between analgesic effect of magnesium sulphate versus dexmedetomidine as an adjuvant to bupivacaine when injected intraperitoneal in abdominal aortic surgery.METHODS:50 patients undergoing abdominal aortic surgery are randemelly divided into 2 groups.(group D:patients received 20ml isobaric bupivacaine+1mic/kg dexemedetomidine completed to 5ml normal saline) Group M:patients received 20ml isobaric bupivacaine+5mg magnesuim sulphate .postoperative VAS,MAP will be recorded initially then every 2hours.
Timeline
- Start
- 2022-10-01
- Primary completion
- 2023-01-01
- Completion
- 2023-01-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | 1 ug/kg | Other |
| Subject | Magnesium Sulfate | Other / unclassified | 500 mg | Other |
| Background | Bupivacaine | Other / unclassified | 0.25 % | Other |
| Background | Bupivacaine | Other / unclassified | 20 ml | Other |
Indications
No indication recorded.