Dexmedetomidine Combined With Bupivacaine for Erector Spinae Plane Block

Phase 1/2 Completed 90 enrolled October 6 University

RandomizedParallel-groupDouble-blindPrevention

Summary

As the posterior lumbosacral spine fixation surgeries are common spine procedures done nowadays due to different causes and as this spine procedure is mostly accompanied with moderate to severe postoperative pain, so it is necessary to find an effective and efficient postoperative analgesia for patients with this surgery.

Timeline

Start: 2022-11-15
Primary completion: 2023-07-01
Completion: 2023-07-20

Publications

Abu El Hassan SHA, Wahsh EA, Mousa AM, Ibrahim ARN, Mohammed EL. Comparative Study Between Dexmedetomidine with Bupivacaine and Bupivacaine Alone in Erector Spinae Plane Block for Postoperative Pain Control of Posterior Lumbosacral Spine Fixation Surgeries: A Randomized Controlled Trial. Drug Des Devel Ther. 2024 Feb 7;18:351-363. doi: 10.2147/DDDT.S444485. eCollection 2024.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Bupivacaine	Other / unclassified	0.25 %	—
Comparator	Bupivacaine	Other / unclassified	20 ml	—
Comparator	Dexmedetomidine	Other / unclassified	1 ug/kg	—

Indications

No indication recorded.