drugset / Trial / NCT05639712
Affective Effects of Pre-surgery Opioids: a Randomized, Doubleblind Placebo-controlled Trial
RandomizedParallel-groupDouble-blindOther
Summary
1. To investigate and compare the affective short-term effects of opioid drugs: morphine, oxycodone and fentanyl, administered to the patients before the induction of general anesthesia. 2. Charting opioid use after surgery in patients treated at hospitals in Norway 3. Identify predictors for postoperative opioid use and persistent pain
Timeline
- Start
- 2022-12-13
- Primary completion
- 2025-05-27
- Completion
- 2025-06-27
Publications
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Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fentanyl | Other / unclassified | 0.025 mg | Intravenous |
| Comparator | Fentanyl | Other / unclassified | 0.05 mg | Intravenous |
| Comparator | Fentanyl | Other / unclassified | 0.1 mg | Intravenous |
| Comparator | Morphine | Other / unclassified | 2.5 mg | Intravenous |
| Comparator | Morphine | Other / unclassified | 5 mg | Intravenous |
| Comparator | Morphine | Other / unclassified | 10 mg | Intravenous |
| Comparator | Oxycodone | Other / unclassified | 2.5 mg | Intravenous |
| Comparator | Oxycodone | Other / unclassified | 5 mg | Intravenous |
| Comparator | Oxycodone | Other / unclassified | 10 mg | Intravenous |