drugset / Trial / NCT05661578

A Study to Evaluate the Safety and Pharmacokinetics of the Intravenous Fixed-Dose Combination (IV FDC) of Tiragolumab and Atezolizumab in Participants With Locally Advanced, Recurrent or Metastatic Solid Tumors

NCT05661578

Phase 2 Completed 64 enrolled Hoffmann-La Roche
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the safety, pharmacokinetics, and immunogenicity of tiragolumab and atezolizumab intravenous fixed-dose combination (IV FDC) in participants with histologically confirmed PD-L1-selected solid tumors whose disease is locally advanced, recurrent, or metastatic and for whom an investigational agent in combination with an anti-PD-L1 antibody is considered an acceptable treatment option.

Timeline

Start
2023-05-04
Primary completion
2025-12-26
Completion
2025-12-26

Drugs

EvaluationDrugModalityDoseRoute
Subject Atezolizumab Monoclonal antibody 1200 mg Intravenous
Subject Tiragolumab Monoclonal antibody 600 mg Intravenous

Indications

No indication recorded.