drugset / Trial / NCT05681039

Phase 2 Trial of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab in Patients With Newly Diagnosed PD-L1 CPS Positive Resectable Stage 3-4 Oral Cavity Squamous Cell Carcinoma (OCSCC).

NCT05681039

Phase 2 Active not recruiting 29 enrolled M.D. Anderson Cancer Center Genentech, Inc. · collab
NaSingle-groupOpen-labelTreatment

Summary

To learn if treatment with tiragolumab and atezolizumab before and after standard of care surgery and chemoradiation (radiation therapy with or without cisplatin/carboplatin) can help to control OCSCC that is PD-L1 CPS positive.

Timeline

Start
2023-06-02
Primary completion
2026-11-01
Completion
2026-11-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Atezolizumab Monoclonal antibody Intravenous
Subject Tiragolumab Monoclonal antibody Intravenous