drugset / Trial / NCT05684276

DUMAS: Neo-Adjuvant Immunotherapy for Pancoast Tumors

NCT05684276 ↗

Phase 2 Active not recruiting 22 enrolled Fundación GECP
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to test the efficacy of induction treatment of immunotherapy and chemotherapy depending on the resection status for the treatment of non small cell lung cancer patients diagnosed with pancoast tumor. The main objectives it aims to answer are: * Complete resection rate after induction treatment with chemotherapy plus nivolumab * Overall Survival and Progression Free Survival at 24 months The sample size is 40 patients.

Timeline

Start
2023-05-12
Primary completion
2028-03-01
Completion
2028-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule 6 unknown Intravenous
Subject Nivolumab Monoclonal antibody 480 mg Intravenous
Subject Paclitaxel Small molecule 200 mg/m2 Other