drugset / Trial / NCT05684276
DUMAS: Neo-Adjuvant Immunotherapy for Pancoast Tumors
NaSingle-groupOpen-labelTreatment
Summary
The goal of this clinical trial is to test the efficacy of induction treatment of immunotherapy and chemotherapy depending on the resection status for the treatment of non small cell lung cancer patients diagnosed with pancoast tumor. The main objectives it aims to answer are: * Complete resection rate after induction treatment with chemotherapy plus nivolumab * Overall Survival and Progression Free Survival at 24 months The sample size is 40 patients.
Timeline
- Start
- 2023-05-12
- Primary completion
- 2028-03-01
- Completion
- 2028-06-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Carboplatin | Small molecule | 6 unknown | Intravenous |
| Subject | Nivolumab | Monoclonal antibody | 480 mg | Intravenous |
| Subject | Paclitaxel | Small molecule | 200 mg/m2 | Other |