drugset / Trial / NCT05775861

Dexmedetomidine Added to Ropivacaine Single Shot vs Continuous Interscalene Nerve Block

NCT05775861 ↗

RandomizedParallel-groupOpen-labelTreatment

Summary

Arthroscopic shoulder surgery is increasingly performed in an outpatient setting and post-operative pain management is often a real challenge as those surgeries are well recognized for their high level of pain which often affects physical rehabilitation. The interscalene block is a largely used anesthetic technique to perform these surgeries whilst avoiding general anesthesia (GA) and to provide postoperative analgesia. However, the painful period often exceeds the duration of a single shot block, thus affecting patient recovery. Some specialized centers use a continuous catheter and elastomeric pump in order to prolong the duration of analgesia. However, several logistical, professional and financial constraints limit the use of these catheters and pumps in a great number of outpatient centers. On the other hand, perineural dexmedetomidine is increasingly used as an adjuvant to improve block onset, analgesia duration and patient satisfaction. The use of adjuvants such as perineural dexmedetomidine added to a single shot interscalene block appears to be an interesting option to prolong postoperative analgesia without the limitations imposed by a continuous catheter and elastomeric pumps in arthroscopic shoulder surgeries.

Timeline

Start
2022-08-23
Primary completion
2025-01
Completion
2025-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 2 ug/kg Other
Subject Ropivacaine Other / unclassified 5 ml Other
Subject Ropivacaine Other / unclassified 150 mg Other
Background Lidocaine Other / unclassified 3 ml —

Indications