drugset / Trial / NCT05834543

Clinical Trial to Evaluate the Safety and Effectiveness of TQB2618 Injection Combined Therapy in Patients With Advanced Esophageal Squamous Cell Carcinoma

NCT05834543

Phase 1/2 Terminated 34 enrolled Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

To investigate the efficacy and safety of TQB2618 injection combined Penpulimab and chemotherapy in the first-line treatment of recurrent/metastatic esophageal squamous cell carcinoma compared with Penpulimab combined chemotherapy. The primary efficacy outcomes are progression free survival (PFS) and objective response rate (ORR).

Timeline

Start
2023-05-26
Primary completion
2024-10-23
Completion
2025-03-03

Drugs

EvaluationDrugModalityDoseRoute
Subject TQB2618 Monoclonal antibody
Subject TQB3617 Unknown
Background Cisplatin Other / unclassified
Background Paclitaxel Small molecule
Background Penpulimab Monoclonal antibody