drugset / Trial / NCT05835011

A Study of Oral Decitabine/Cedazuridine in Combination With Magrolimab in Participants With Intermediate- to Very High-Risk Myelodysplastic Syndromes (MDS)

NCT05835011

Phase 2 Terminated 2 enrolled Astex Pharmaceuticals, Inc.
NaSingle-groupOpen-labelTreatment

Summary

The primary purpose of the study is to evaluate the preliminary safety and efficacy of oral decitabine/cedazuridine in combination with magrolimab.

Timeline

Start
2023-06-27
Primary completion
2023-08-21
Completion
2023-08-21

Drugs

EvaluationDrugModalityDoseRoute
Subject Cedazuridine Small molecule 100 mg Oral
Subject Decitabine Small molecule 35 mg Oral
Subject Magrolimab Monoclonal antibody 30 mg/kg Intravenous