drugset / Trial / NCT05835713
Total Intravenous Anesthesia for Rigid Bronchoscopy Using Remimazolam
Withdrawn
Samsung Medical Center
RandomizedParallel-groupSingle-blindTreatment
Summary
Rigid bronchoscopy usually requires deep general anesthesia, but the duration of the procedure is relatively short. Remimazolam, a recently developed anesthetics, showed faster recovery from anesthesia and stable hemodynamics compared to propofol, the most popular anesthetics. However, few studies have investigated the usefulness of remimazolam for rigid bronchoscopy. Therefore, the investigators compared the usefulness of propofol and remimazolam in total intravenous anesthesia for rigid bronchoscopy.
Timeline
- Start
- 2023-04
- Primary completion
- 2024-04
- Completion
- 2024-04
Outcome
Outcome not reported
Stopped (Enrollment): “Identically designed study had been published before enrollment of first participant. Therefore, this study was not started. The IRB was approved the withdrawn of the study.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propofol | Small molecule | 4 mg/kg | Intravenous |
| Comparator | Propofol | Small molecule | 8 mg/kg | Intravenous |
| Subject | Remimazolam | Small molecule | 1 mg/kg | Intravenous |
| Background | Flumazenil | Small molecule | 0.5 mg | — |
| Background | Remifentanil | Small molecule | 0.05 ug/kg | Intravenous |
| Background | Remifentanil | Small molecule | 0.15 ug/kg | Intravenous |