drugset / Trial / NCT05835713

Total Intravenous Anesthesia for Rigid Bronchoscopy Using Remimazolam

NCT05835713

RandomizedParallel-groupSingle-blindTreatment

Summary

Rigid bronchoscopy usually requires deep general anesthesia, but the duration of the procedure is relatively short. Remimazolam, a recently developed anesthetics, showed faster recovery from anesthesia and stable hemodynamics compared to propofol, the most popular anesthetics. However, few studies have investigated the usefulness of remimazolam for rigid bronchoscopy. Therefore, the investigators compared the usefulness of propofol and remimazolam in total intravenous anesthesia for rigid bronchoscopy.

Timeline

Start
2023-04
Primary completion
2024-04
Completion
2024-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Propofol Small molecule 4 mg/kg Intravenous
Comparator Propofol Small molecule 8 mg/kg Intravenous
Subject Remimazolam Small molecule 1 mg/kg Intravenous
Background Flumazenil Small molecule 0.5 mg
Background Remifentanil Small molecule 0.05 ug/kg Intravenous
Background Remifentanil Small molecule 0.15 ug/kg Intravenous