drugset / Trial / NCT05861791

Comparison of Patient-controlled Analgesia Regimenfor Postoperative Pain in Patients Undergoing Total Knee Arthroplasty

NCT05861791

RandomizedParallel-groupSingle-blindSupportive care

Summary

Patients who undergoing total knee arthroplasty under spinal analgesia will be recruited and randomly assigned to the following two groups according to the regimen of PCA: (A) opioid group who receive only fentanyl citrate 1200mcg for continuous infusion drug, (B) non-opioid group who receive ketorolac tromethamine 150mg with nefopam hydrochloride 100mg for continuous infusion drug. All the patients will receive additional fentanyl citrate as bolus injection drug if they need more analgesics postoperatively.

Timeline

Start
2023-02-07
Primary completion
2024-07-12
Completion
2024-07-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Fentanyl Other / unclassified 1200 ug Intravenous
Comparator Ketorolac Other / unclassified 150 mg Intravenous
Comparator Nefopam Small molecule 100 mg Intravenous

Indications

No indication recorded.