drugset / Trial / NCT05863845
Efficacy and Safety of Venetoclax Combined With BEAM Pretreatment in Autologous Transplantation for DLBCL
RandomizedParallel-groupOpen-labelTreatment
Summary
This single-center, randomized clinical study will evaluate the efficacy and safety of Venetoclax combined with BEAM Pretreatment Regimen in ASCT treatment of DLBCL patients.
Timeline
- Start
- 2023-06-01
- Primary completion
- 2024-11-30
- Completion
- 2025-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Venetoclax | Small molecule | 800 mg | Oral |
| Background | Cytarabine | Small molecule | 100 mg/m2 | Intravenous |
| Background | Etoposide | Small molecule | 200 mg/m2 | Intravenous |
| Background | Melphalan | Small molecule | 140 mg/m2 | Intravenous |
| Background | carmustine | Small molecule | 300 mg/m2 | Intravenous |