Comparison of Hemodynamic Stability During Anesthesia Using Remimazolam and Sevoflurane in Minimally Invasive AVR

Summary

Anesthetic agents can cause hypotension, and be especially dangerous in patients with severe aortic stenosis, which can lead to even circulatory collapse. Remimazolam is known for its hemodynamic stability compared to propofol. This study is designed to compare effects of remimazolam vs. sevoflurane anesthesia on intraoperative hemodynamics in patients with severe aortic valve stenosis.

Timeline

Start

2023-06-29

Primary completion

2025-06-10

Completion

2025-06-10

Publications

• Lee J, Shin SW, Yoon JU, Kim HJ, Yoon JP, Shon HS, Lee DE, Kim HY. Vasopressor requirements and hemodynamic stability during anesthesia using remimazolam and sevoflurane in patients undergoing minimally invasive aortic valve replacement surgery: a prospective randomized controlled study. J Thorac Dis. 2026 Apr 30;18(4):342. doi: 10.21037/jtd-2026-1-0072. Epub 2026 Mar 27.

Drugs

Indications