Adjuvant Dexmedetomidine and Tramadol in Subcostal Transversus Abdominis Plan Block

Completed 60 enrolled Yuzuncu Yil University

RandomizedParallel-groupSingle-blindScreening

Summary

In this study, dexmedetomidine and tramadol were added as adjuvant to bupivacaine in transversus abdominis plane block (TAP), intraoperative hemodynamics, opioid consumption, muscle relaxant use, postoperative analgesic effects and side effects (such as nausea-vomiting) were evaluated.

Timeline

Start: 2022-03-01
Primary completion: 2023-03-01
Completion: 2023-04-03

Outcome

Missed primary endpoint

paper did not have superiority over each other in terms of postoperative analgesia time, analgesic consumption, side effect profile, and mobilization times (p > 0.05). PMID 38002616 ↗

Publications

Korkutata Z, Tekeli AE, Kurt N. Intraoperative and Postoperative Effects of Dexmedetomidine and Tramadol Added as an Adjuvant to Bupivacaine in Transversus Abdominis Plane Block. J Clin Med. 2023 Nov 9;12(22):7001. doi: 10.3390/jcm12227001.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Tramadol	Other / unclassified	1.5 mg/kg	—
Background	Bupivacaine	Other / unclassified	0.25 %	—

Indications

No indication recorded.