drugset / Trial / NCT05914389
Induction Chemotherapy Combined With Neoadjuvant Immunotherapy for MSS Colon Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
This study aims to elucidate the regression effects of neoadjuvant chemotherapy combined with immunotherapy and adjuvant therapy in locally advanced MSS colon cancer.
Timeline
- Start
- 2023-08
- Primary completion
- 2025-08
- Completion
- 2030-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Clostridium butyricum | Other / unclassified | 160 mg | Oral |
| Subject | Envafolimab | Monoclonal antibody | 100 mg | — |
| Background | Capecitabine | Small molecule | 1000 mg/m2 | Oral |
| Background | Oxaliplatin | Small molecule | 130 mg/m2 | — |