drugset / Trial / NCT05988671

Intraperitoneal Dexamethasone, Dexmedetomidine, and Dexamethasone-Dexmedetomidine Combination on Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

NCT05988671

Phase 3 Completed 120 enrolled Al-Azhar University Benha University · collab
RandomizedParallel-groupTriple-blindPrevention

Summary

Nausea and vomiting are some of the most common complaints of patients after any anesthesia, which is often associated with postop-erative pain. The double-blind clinical trial study aimed to compare the prophylactic effect of dexamethasone and dexmedetomidine and their combination in reducing postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy.

Timeline

Start
2023-08-10
Primary completion
2024-08-30
Completion
2024-08-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexamethasone Small molecule 8 mg Intravenous
Comparator Dexmedetomidine Other / unclassified 1 ug/kg Intravenous

Indications