drugset / Trial / NCT06040489
Pilot Study: Oral Treatment of American Tegumentary Leishmaniasis (Cutaneous and Mucosal Forms) in the Elderly
RandomizedParallel-groupOpen-labelTreatment
Summary
Randomised clinical trial comparing oral miltefosine associated with pentoxifylline to intravenous liposomal amphotericin b for the treatment of cutaneous and mucosal leishmaniasis
Timeline
- Start
- 2022-06-22
- Primary completion
- 2024-06
- Completion
- 2026-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amphotericin B | Unknown | 25 mg/kg | Intravenous |
| Comparator | Amphotericin B | Unknown | 40 mg/kg | Intravenous |
| Subject | Miltefosine | Small molecule | 50 mg | Oral |
| Subject | Pentoxifylline | Small molecule | 400 mg | Oral |