drugset / Trial / NCT06054906

Neoadjuvant of Sintilimab Combined Weekly Metronomic Chemotherapy (PLOF) for Resectable Locally Advanced Gastric Cancer

NCT06054906 ↗

Phase 2 Recruiting 50 enrolled Huashan Hospital
NaSingle-groupOpen-labelTreatment

Summary

To evaluate efficacy and safety of Neoadjuvant of Sintilimab Combined Weekly Metronomic Chemotherapy (PLOF) in resectable locally advanced gastric cancer.

Timeline

Start
2023-10-18
Primary completion
2025-06-30
Completion
2025-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Oxaliplatin Small molecule 50 mg/m2 —
Subject Paclitaxel Small molecule 60 mg/m2 —
Subject Sintilimab Monoclonal antibody 200 mg Intravenous
Subject fluorouracil Small molecule 425 mg/m2 —

Indications