drugset / Trial / NCT06080724
Efficacy of Intralesional Bleomycin Alone and in Combination With Dexamethasone in Infantile Haemangiomas
RandomizedParallel-groupDouble-blindTreatment
Summary
Objective: This study is intended to compare the outcome of intralesional bleomycin with dexamethasone versus the bleomycin alone in infantile haemangioma. Materials and Methods: This RCT was performed after the ethical approval at the pediatric surgery department of KEMU/Mayo hospital Lahore. 114 patients were enrolled in two groups A and B. Both groups contained 57 patients each. Group A was administered intralesional bleomycin with dexamethasone and group B was given intralesional bleomycin alone with a space of 4 weeks. Selection of patients was made according to inclusions and exclusion criteria.
Timeline
- Start
- 2021-03-22
- Primary completion
- 2021-12-02
- Completion
- 2022-03-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bleomycin | Unknown | 0.5 mg/kg | Other |
| Subject | Bleomycin | Unknown | 1 mg/kg | Other |
| Subject | Dexamethasone | Small molecule | 0.8 mg/kg | Other |
| Subject | Dexamethasone | Small molecule | 1.6 mg/kg | Other |