drugset / Trial / NCT06110546
Impact of Methadone on Prolonged Mechanical Ventilation in Patients on Continuous Treatment With Opioids
RandomizedParallel-groupSingle-blindOther
Summary
The purpose of this study is to determine the effect of methadone on the duration on mechanical ventilation in critically ill patients receiving more than 72 hours of mechanical ventilation (MV) by comparing the number of ventilator free days from enrollment to the time of discharge, to assess the safety of methadone administration in critically ill patients while in the hospital and to determine hospital length of stay from the time of enrollment to the time of discharge
Timeline
- Start
- 2024-02-18
- Primary completion
- 2024-02-22
- Completion
- 2024-02-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methadone | Other / unclassified | 5 mg | — |
| Subject | Methadone | Other / unclassified | 10 mg | — |
| Subject | Methadone | Other / unclassified | 15 mg | — |
| Comparator | Fentanyl | Other / unclassified | — | Intravenous |
| Comparator | Hydromorphone | Other / unclassified | — | — |
Indications
No indication recorded.