drugset / Trial / NCT06135584

Study on MAFLD-related Cirrhosis Prevention and Treatment Strategies

NCT06135584

Non-randomizedParallel-groupOpen-labelTreatment

Summary

To establish a prospective, multicenter, biopsie-confirmed clinical cohort of MAFLD-related cirrhosis (F3-F4) in China, and analyze the clinical, histopathological features and natural outcomes of MAFLD-associated liver fibrosis/cirrhosis in China. And than to conducted a real-world study of different strategies of Chinese characteristics for the prevention and treatment of MAFLD-related cirrhosis to evaluate the efficacy and safety of the strategies.

Timeline

Start
2023-11-18
Primary completion
2026-12-31
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Metformin Small molecule 500 mg
Subject Pioglitazone Small molecule 15 mg