drugset / Trial / NCT06145191
Prophylactic Tranexamic Acid Versus Adrenaline During Flexible Bronchoscopy
RandomizedParallel-groupDouble-blindPrevention
Summary
Endobronchial bleeding is a common complication of bronchoscopy. Major bleeding, although rare, can be life threatening and often requires advanced therapeutic interventional pulmonary procedures which are not widely available. Minor bleeding can negatively impact outcomes such as diagnostic yield, sample size and bronchoscopy duration. Both adrenaline and tranexamic acid are successfully used topically for hemostasis during diagnostic bronchoscopy. The aim of this study is to evaluate the efficacy of prophylactically applied adrenaline and tranexamic acid in bleeding prevention during diagnostic bronchoscopy.
Timeline
- Start
- 2023-12-18
- Primary completion
- 2025-03-28
- Completion
- 2025-03-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Epinephrine | Other / unclassified | 2 ml | Topical |
| Subject | Tranexamic Acid | Small molecule | 2 ml | Topical |
| Subject | Tranexamic Acid | Small molecule | 100 mg | Topical |