drugset / Trial / NCT06165068

Effects of Antiplatelet and Antioxidant Agents on Drusen Progression: A Pilot, Prospective Cohort Study

NCT06165068

Phase 3 Recruiting 174 enrolled Navamindradhiraj University
Non-randomizedParallel-groupOpen-labelPrevention

Summary

The aim of this clinical trial is to evaluate the effect of low doses of antiplatelet medications (aspirin 81 mg/day or clopidogrel 75 mg/day) with or without a combination of antioxidants (N-acetylcysteine 600 mg/day) in a dry AMD patient with large drusen. Participants will divided in to three groups. * Participants who were already taking low dose antiplatelet medications. * Participants who take the antiplatelet drug mentioned above in addition to the antioxidant prescribed by the investigator * Participants does not use any medications.

Timeline

Start
2023-12
Primary completion
2025-12
Completion
2026-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Aspirin Small molecule 81 mg
Subject Clopidogrel Small molecule 75 mg
Subject N-acetylcysteine Small molecule 600 mg