Impact of Desflurane and Sevoflurane on Postoperative Delirium in Elderly Patients

Summary

Advanced age is a consistent risk factor for the incidence of postoperative cognitive decline, which is associated with longer hospital stays, decreased quality of life, and increased mortality. Anaesthetic drugs can also affect postoperative cognition, as their residual effects can alter central nervous system activity. Desflurane and sevoflurane are widely used volatile anesthetics. Choice anesthetics may influence the occurrence of postoperative delirium. However, evidence in this aspect is conflicting.

Timeline

Start

2023-09-10

Primary completion

2025-07

Completion

2025-09

Drugs

Indications