drugset / Trial / NCT06207799

Pre-transplant Purging and Post-transplant MRD-guided Maintenance Therapy With Elranatamab in Patients With High-risk Multiple Myeloma

NCT06207799

Phase 2 Recruiting 40 enrolled M.D. Anderson Cancer Center Pfizer · collab
NaSingle-groupOpen-labelTreatment

Summary

To learn if giving elranatamab before and after an autologous stem cell transplant (ASTC) can help to control newly diagnosed, high-risk MM. An ASTC is a type of transplant in which a person's own stem cells are collected, preserved, and returned to them.

Timeline

Start
2024-07-17
Primary completion
2029-12-31
Completion
2031-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Elranatamab Monoclonal antibody Subcutaneous
Subject Lenalidomide Other / unclassified Oral
Background Busulfan Small molecule Oral
Background G-CSF Unknown Intravenous
Background Melphalan Small molecule Intravenous
Background Plerixafor Small molecule Subcutaneous

Indications