drugset / Trial / NCT06231043

Diclofenac IM Versus Tramadol IV in Acute Renal Colic, RCT

NCT06231043

Phase 4 Completed 68 enrolled Lampang Hospital
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Patients presented with acute pain from renal colic, the standard of care are prescribed NSAIDs, most common drug used is intramuscular (IM) Diclofenac injected at the gluteal muscle. Due to adverse effects in some patients, the nursing council has banned the injection by nurses. Since then, there has been a change in treatment by using intravascular (IV) Tramadol. According to various research, Diclofenac has a higher efficacy in controlling pain compared to other medications. In clinical practice, Tramadol has less efficacy of decreasing pain and a longer onset of action. At presence, there has been no research performed comparing the efficacy between these two drugs especially from the viewpoint of time dimension.

Timeline

Start
2022-04-27
Primary completion
2023-03-31
Completion
2023-04-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Diclofenac Other / unclassified 75 mg Intramuscular
Subject Tramadol Other / unclassified 50 mg Intravenous

Indications

No indication recorded.