drugset / Trial / NCT06251973

A Study of agenT-797 in Combination With Botensilimab, Balstilimab, Ramucirumab, and Paclitaxel for People With Esophageal, Gastric, or Gastro-esophageal Junction Cancer

NCT06251973

Phase 2 Active not recruiting 20 enrolled Memorial Sloan Kettering Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

Participants will receive study treatment with agenT-797, botensilimab, balstilimab, ramucirumab, and paclitaxel. When participants start each agent will depend on how their disease is affecting them.

Timeline

Start
2024-02-01
Primary completion
2027-08-01
Completion
2027-08-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Balstilimab Monoclonal antibody Intravenous
Subject Botensilimab Monoclonal antibody
Subject agenT-797 Cell therapy
Background Paclitaxel Small molecule
Background Ramucirumab Monoclonal antibody