drugset / Trial / NCT06253702
Brain Blood Flow Responses to Stress: Sex Differences
Phase 4
Completed
22 enrolled
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI) · collab
RandomizedFactorialDouble-blindBasic science
Summary
Twenty-six otherwise healthy adults between 18-40 years of age composed of 13 males and 13 females will be enrolled in this study to determine how sex and sex hormones influence cerebral blood flow (CBF) control in healthy young adults without confounds of age or disease. Participants can expect to be on study for approximately 16 days.
Timeline
- Start
- 2024-07-24
- Primary completion
- 2025-05-31
- Completion
- 2025-05-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Estradiol | Other / unclassified | 2 mg | Oral |
| Subject | Indomethacin | Small molecule | — | — |
| Subject | Testosterone | Small molecule | 50 mg | — |
| Background | Anastrozole | Other / unclassified | 1 mg | — |
| Background | Elagolix | Small molecule | 200 mg | — |