drugset / Trial / NCT06331598

A Study of Adjuvant Atezolizumab or Atezolizumab Plus Tiragolumab in Solid Tumors with Resectable Disease with Intermediate-High Risk of Recurrence and High Tumor Mutational Burden (TMB-H) or Microsatellite Instability (MSI-H)

NCT06331598

Phase 2 Withdrawn Hoffmann-La Roche
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is being conducted to evaluate efficacy parameters (disease free survival \[DFS\] and overall survival \[OS\]) of atezolizumab and atezolizumab in combination with tiragolumab in TMB-H or MSI-H as adjuvant treatment after standard radical intended treatment in participants with intermediate-high risk of recurrence.

Timeline

Start
2024-11-30
Primary completion
2028-10-20
Completion
2029-09-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Atezolizumab Monoclonal antibody 1680 mg Intravenous
Subject Tiragolumab Monoclonal antibody 840 mg Intravenous

Indications