drugset / Trial / NCT06344403
Clinical Efficacy and Safety of Tender Point Infiltration (TPI) for Acute and Subacute Zoster Associated Pain
RandomizedCrossoverOpen-labelTreatment
Summary
Herpes zoster (HZ) is a skin infection disease which cause severe zoster-associated pain (ZAP) along sensory nerve in the corresponding segment. Evidence for the efficacy of existing local therapies for acute/subacute ZAP is limited. The hypothesis is that patients with acute/subacute ZAP treated with TPIs with local anesthetic and steroids under the basis of standard treatment will show better clinical outcomes compared with subjects treated with standard antiviral medicine treatment only.
Timeline
- Start
- 2025-06-01
- Primary completion
- 2026-10-01
- Completion
- 2027-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lidocaine | Other / unclassified | — | Other |
| Subject | betamethasone dipropionate | Small molecule | — | Other |
| Background | Celecoxib | Other / unclassified | 200 mg | Oral |
| Background | Pregabalin | Small molecule | 300 mg | Oral |
| Background | Tramadol | Other / unclassified | 100 mg | Oral |