drugset / Trial / NCT06390787

The Efficacy of B6 and Metoclopramide Combination in Comparison With the Other Antiemetics

NCT06390787

Phase 2/3 Completed 250 enrolled University of Baghdad
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study investigates the effectiveness of combining vitamin B6 (pyridoxine) and metoclopramide compared to standard antiemetic treatments for managing nausea and vomiting. Through a prospective, randomized controlled trial involving adult patients with diverse causes of nausea and vomiting, we aim to evaluate the frequency, severity, and tolerability of the B6 and metoclopramide combination. By elucidating its comparative efficacy against established antiemetics, this research seeks to provide evidence-based guidance for clinicians in selecting optimal treatment regimens tailored to individual patient needs, ultimately enhancing the management of nausea and vomiting across various medical conditions.

Timeline

Start
2024-01-30
Primary completion
2024-04-20
Completion
2024-04-21

Drugs

EvaluationDrugModalityDoseRoute
Comparator Metoclopramide Small molecule
Comparator Ondansetron Other / unclassified
Comparator Pyridoxine Unknown

Indications

No indication recorded.