drugset / Trial / NCT06395727

Effect of Topical Airway Block on Hemodynamic Stability Post Induction of Anaesthesia in Cardiac Surgeries

NCT06395727 ↗

Phase 4 Completed 106 enrolled Ain Shams University
RandomizedParallel-groupSingle-blindPrevention

Summary

Opioids have always been the mainstay in management of patients during cardiac surgeries. Mega doses are often used to relieve stress of surgeries in highly labile patients with narrow hemodynamic threshold to keep the balance between oxygen demand and supply. Unfortunately, this is associated with hemodynamic instability and affect the fast-track pathway for extubation. Most of these doses are given in induction, so by blocking airway by non-invasive technique, this will help in the reduction in opioid doses and preventing risky hemodynamic instability during induction of anesthesia in these patients.

Timeline

Start
2024-04-25
Primary completion
2024-11-13
Completion
2024-12-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Fentanyl Other / unclassified 1 ug/kg —
Subject Fentanyl Other / unclassified 3 ug/kg —
Subject Fentanyl Other / unclassified 5 ug/kg —
Subject Lidocaine Other / unclassified 5 ml Inhaled
Subject Lidocaine Other / unclassified 200 mg Inhaled

Indications

No indication recorded.