drugset / Trial / NCT06452147
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
Recruiting
1860 enrolled
Second Affiliated Hospital of Wenzhou Medical University
Affiliated Wenling Hospital of Wenzhou Medical University · collabDongyang People's Hospital · collabFirst Affiliated Hospital of Wenzhou Medical University · collabJinhua Municipal Central Hospital · collabLishui Country People's Hospital · collabNingbo No.2 Hospital · collabNingbo No.6 Hospital · collabPeople's Hospital of Quzhou · collabTaizhou Hospital · collabTaizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University · collabThe Fifth Hospital Affiliated to Wenzhou Medical University/ Lishui Central Hospital · collabZhejiang Provincial People's Hospital · collab
RandomizedParallel-groupOpen-labelPrevention
Summary
Anesthesia and perioperative Neurocognitive Disorders in the Elderly patients undergoing hip fracture Surgery platform trial (ANDES platform trial): A pragmatic multi-arm, adaptive, open label, multicenter randomized controlled platform trial to assess the effect of different enhance anesthesia technique in perioperative neurocognitive function, as compared to standard anesthesia care in the elderly patients undergoing hip fracture
Timeline
- Start
- 2024-06-19
- Primary completion
- 2028-07-30
- Completion
- 2028-07-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bupivacaine | Other / unclassified | 133 mg | — |
| Subject | Lidocaine | Other / unclassified | 1 mg/kg | Intravenous |
| Subject | Lidocaine | Other / unclassified | 2 mg/kg | Intravenous |