NCT06465992: Liposomal Bupivacaine With Dexamethasone for Foot Surgery

Summary

This study aims to understand the ideal formulation to utilize in saphenous nerve and popliteal nerve blocks for foot and ankle procedures. It will examine the use of liposomal bupivacaine alone or liposomal bupivacaine with dexamethasone prior to foot and ankle procedures in peripheral nerve blocks. We will compare liposomal bupivacaine (Exparel) and liposomal bupivacaine (Exparel) combined with dexamethasone to determine if the addition of dexamethasone significantly decreases postoperative narcotic use and prolongs analgesic effects when administered in a popliteal and saphenous block prior to foot and ankle orthopedic procedures.

Timeline

Start: 2024-06-17
Primary completion: 2025-06-30
Completion: 2025-06-30

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Bupivacaine	Other / unclassified	266 mg	Other
Comparator	Dexamethasone	Small molecule	10 mg	Other
Comparator	Bupivacaine	Other / unclassified	10 ml	Other

Indications

No indication recorded.