drugset / Trial / NCT06547203

Cetuximab, Irinotecan, Toripalimab in RAS/BRAF Wild-type Ultraselected Right-sided Colorectal Cancer Study

NCT06547203 ↗

Phase 2 Recruiting 34 enrolled Sun Yat-sen University
NaSingle-groupOpen-labelTreatment

Summary

The objective of this clinical trial is to evaluate the efficacy and safety of cetuximab combined with PD-1 inhibitor and irinotecan in negative ultraselection RAS/BRAF wild-type refractory right-sided metastatic colorectal cancer.

Timeline

Start
2024-07-18
Primary completion
2026-07-30
Completion
2029-07-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Cetuximab Monoclonal antibody 500 mg/m2 Intravenous
Subject Irinotecan Small molecule 150 mg/m2 Intravenous
Subject Toripalimab Monoclonal antibody 3 mg/kg Intravenous

Indications