drugset / Trial / NCT06548763

Oral Topotecan With Toripalimab for Patients With Endometrial Cancer

NCT06548763

Phase 2 Not yet recruiting 30 enrolled Fudan University
NaSingle-groupOpen-labelTreatment

Summary

This study aims to explore the safety and efficacy of oral topotecan combined with toripalimab in treating advanced/recurrent endometrial cancer through a single-center, prospective, single-arm, phase II clinical trial. The goal is to explore the first-line treatment options for endometrial cancer patients in the era of immunotherapy, to improve the overall treatment level and prognosis of endometrial cancer.

Timeline

Start
2024-11-30
Primary completion
2026-06-30
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Topotecan Small molecule 1.4 mg/m2 Oral
Subject Toripalimab Monoclonal antibody 240 mg Intravenous

Indications