drugset / Trial / NCT06548763
Oral Topotecan With Toripalimab for Patients With Endometrial Cancer
NaSingle-groupOpen-labelTreatment
Summary
This study aims to explore the safety and efficacy of oral topotecan combined with toripalimab in treating advanced/recurrent endometrial cancer through a single-center, prospective, single-arm, phase II clinical trial. The goal is to explore the first-line treatment options for endometrial cancer patients in the era of immunotherapy, to improve the overall treatment level and prognosis of endometrial cancer.
Timeline
- Start
- 2024-11-30
- Primary completion
- 2026-06-30
- Completion
- 2026-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Topotecan | Small molecule | 1.4 mg/m2 | Oral |
| Subject | Toripalimab | Monoclonal antibody | 240 mg | Intravenous |