drugset / Trial / NCT06576830
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
Phase 4
Recruiting
440 enrolled
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · collabNational Institutes of Health (NIH) · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.
Timeline
- Start
- 2024-11-21
- Primary completion
- 2028-12-31
- Completion
- 2029-06-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fentanyl | Other / unclassified | — | — |
| Comparator | Hydromorphone | Other / unclassified | — | — |
| Comparator | Methadone | Other / unclassified | 0.15 mg/kg | Intravenous |
| Comparator | Methadone | Other / unclassified | 0.2 mg/kg | Intravenous |
| Comparator | Methadone | Other / unclassified | 0.25 mg/kg | Intravenous |