drugset / Trial / NCT06602466

A Clinical Study Investigating the Effect of an Experimental Toothpaste Containing Stannous Fluoride in Improving Gingival Health

NCT06602466

Completed 175 enrolled HALEON
RandomizedParallel-groupSingle-blindTreatment

Summary

The aim of this 4-week clinical study is to evaluate the ability of an experimental toothpaste, containing 0.454 percent (%) Stannous Fluoride (SnF2), 0.3% Zinc Chloride (ZnCl2) and 1% Alumina, to improve gingival health and plaque accumulation compared to a regular fluoride toothpaste (negative control) in participants with plaque-induced mild to moderate gingivitis.

Timeline

Start
2024-09-23
Primary completion
2024-12-13
Completion
2024-12-13

Drugs

EvaluationDrugModalityDoseRoute
Comparator Colgate Cavity Protection Toothpaste Unknown 1450 ppm Topical
Subject Zinc Sulfate Unknown 0.3 % Topical
Subject stannous fluoride Small molecule 0.454 % Topical

Indications